Meeting Banner
Abstract #0227

Dual Heart-Phase Cardiac DTI Using Local-Look STEAM

SUMMA25Christian Torben Stoeck1, Nicolas Toussaint2, Peter Boesiger1, Sebastian Kozerke1, 2

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 2Imaging Sciences, King's College London, London, United Kingdom

Analysis of diffusion tensor imaging of the myocardium reveals insight into cardiac mechanics. Previous studies investigated myocardial architecture at different states of cardiac contraction in ex-vivo animal hearts or by interpreting the strain tensor. In this study we present an initial direct comparison of systolic vs. diastolic fiber architecture of the in-vivo human heart based on diffusion weighted images acquired at both time points during the cardiac cycle using a local-look STEAM sequence.

Keywords

achieved acquisitions addressed adjusted analyses analyzing apex apical applying architecture array axis basal biomedical blue bottom cardiac channel cine clinical coding college color considerably contraction contribute corresponds covering crushers defined depth described detected determined deviation diastole diastolic diffusion distribution dual duration eigenvector either encoding engineering entire equatorial essential evolved excitation feasibility fiber field fields fitted five fixated furthermore gating gradient gradients greater guarantee heart hearts helix human humans in vivo initial institute interpolated interpolation investigate king length linearly little local long look magnitude manually might mural myocardial organs partial past path peak periods peter play positions post processing pulse quality readout receiver recent reconstructed reconstruction reconstructions reduced reduction registered related remained remaining reorientation replaced represents resolution respiratory rest role sampling schematic sciences selective shear sheet sheets shimming short shortening shot significantly slew slice slices steam strength studies subsequently system systole systolic tensor tensors thickening third timing understand ventricular view views volume whole window